C. tetani TeNT Light Chain Antibodies

Antibodies that detect C. tetani TeNT Light Chain can be used in several scientific applications, including Immunoprecipitation and Western Blot. This Mouse monoclonal antibody targets C. tetani TeNT Light Chain, and has been validated in experiments with 1 image featured in our data gallery.... Antibodies that detect C. tetani TeNT Light Chain can be used in several scientific applications, including Immunoprecipitation and Western Blot. This Mouse monoclonal antibody targets C. tetani TeNT Light Chain, and has been validated in experiments with 1 image featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF,... Antibodies that detect C. tetani TeNT Light Chain can be used in several scientific applications, including Immunoprecipitation and Western Blot. This Mouse monoclonal antibody targets C. tetani TeNT Light Chain, and has been validated in experiments with 1 image featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies... Antibodies that detect C. tetani TeNT Light Chain can be used in several scientific applications, including Immunoprecipitation and Western Blot. This Mouse monoclonal antibody targets C. tetani TeNT Light Chain, and has been validated in experiments with 1 image featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. Custom conjugation and purification services are available as well.

Target Information

Tetanus toxin, a member of the peptidase M27 family of proteins, is produced by the anaerobic spore-forming bacteria Clostridium tetani as a single-chain polypeptide that is 1315 amino acids (aa) in length. The protein is subsequently cleaved by an endogenous protease to yield the 52 kDa tetanus toxin light chain (TeNT-LC), which is 457 aa in length, and the 98 kDa tetanus toxin heavy chain that is 858 aa long. The light and heavy chains are linked by a disulfide bridge and are non-toxic after separation. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neural synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the ¿76-Gln- -Phe-77¿ bond of synaptobrevin-2.

Synonyms

TeNT-LC; Tentoxylysin; tetX

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Invitrogen

C. tetani TeNT Light Chain Monoclonal Antibody (604023)

Invitrogen

C. tetani TeNT Light Chain Monoclonal Antibody (604023)

Target

Bacteria

Details

Mouse Monoclonal

Application

WB IP

Price

Cat # MA5-24273

100 µg

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C. tetani TeNT Light Chain Antibodies

Target Information

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